Profesor UC3M

Dra. Lorena Cussó Mula

Dra. Lorena
Cussó Mula


I received my PhD from UNED in 2014, and currently I am a visiting lecture at UC3M. My research interests cover areas like small animal imaging, infectious and inflammatory diseases. Summarizing my incipient scientific career in numbers, since 2008 I have worked on 17 research projects, six of them supported byt the ISCIII, three were international projects and three projects of technology transfer. I've been author or co-author of 13 articles ISI journals and about 30 presentations at national and international conferences. Also, I've organized a National workshop in preclinical molecular imaging in colaboration with the UC3M and the IiSGM. 



Bachelor degree

Biomedical Engineering (in English). Universidad Carlos III de Madrid:

  • From edition 2012/13: “Anatomy and Physiology I” and "Anatomy and Physiology II" 
  • From edition 2013/14: “Anatomy and Physiology I” and "Anatomy and Physiology II" 
  • From edition 2014/15: “Anatomy and Physiology I” and "Anatomy and Physiology II" 
  • From edition 2015/16: “Anatomy and Physiology I” and "Anatomy and Physiology II" 
  • From edition 2016/17: “Anatomy and Physiology I” and "Anatomy and Physiology II" 
  • From edition 2017/18: “Anatomy and Physiology I” and "Anatomy and Physiology II" 
  • From edition 2018/19: “Medical Physiology I” (coordinator) and "Medical Physiology II" 

Bachelor Thesis directed

  • Validation of the use of goat’s milk exosomes asa theragnostic platform in oncology, Universidad Carlos III de Madrid. Marina Cañadas Ortega. 2018
  • Dynamic contrast iamging: protocol optimization. María Gómez de Salazar Cordero. Universidad Carlos III de Madrid. 2014
  • Response to deep brain stimulation in the medial prefrontal cortez in a rat model of Schizophrenia: in vivo assessment of brain glucose metabolism. Laura Rodriguez Martin. 2014
  • Evaluación del mejor tratamiento, un bloqueante de canales de calcio o una dieta rica en grasas, en la reducción de captación de FDG por parte del músculo cardiaco. Pablo Sánchez López. Universidad Autónoma de Madrid. 2013


  Máster Universitario en Ingeniería Clínica. Universidad Carlos III de Madrid (2018-2019):

  • Sistemas fisiológicos (coordinator and teacher)
  • Ingeniería de procesos y gestión de servicios hospitalarios (coordinator)
  • Gestión económica y organización del sistema sanitario y de las instalaciones hospital (coordinator)                                                                                                                                                                                     

​Máster universitario de investigación en medicina traslacional. Universidad Complutense de Madrid (2017-2019):

  • Imagen en Biomedicina (teacher)

Postgrado en Infraestructuras, Equipamiento y Manteniemiento de Establecimientos de Salud. Universidad Carlos III de Madrid (2014-2015):

  • Módulo II: Gestión Tecnológica del Equipamiento (teacher)

Master Thesis directed

  • Puesta a punto de un modelo murino de Infección por Clostridium difficile y su evaluación por técnicas de imagen PET-CT. Universidad Autónoma de Madrid. Ana Villarejo López. 2015


  • Curso de Técnicas Experimentales en Investigación Biomédica (1ª, 2ª y 3ª Edición). Instituto de Investigación Sanitaria Gregorio Marañón: Seminario sobre "Cell-Tracking" mediante Imagen Molecular. 
  • Advanced Course of Magnetic Resonance Lung Imaging Using Hyperpolarized Gases, 26-30 mayo de 2008. PHeLINet

Selected Publications


  • Cussó L, Desco M. Suppression of 18F-FDG signal in the bladder on small animal PET-CT. PLOS ONE 13(10): e0205610, 2018
  • Salinas B, Guembe M, Cussó L, Kestler M, Guinea J, Desco M, Muñóz P, Bouza E. Assessment of the Anti-Biofilm Effect of Micafungin in an Animal Model of Catheter-Related Candidemia. Medical Mycology, 2018
  • García Romero A, Desco M, Cussó L, Blanch Lluis, Pinilla B. Guía para el análisis de la innovación en hospitales. Proyecto seleccionado en el Programa de Innovación Abierta 2016 de COTEC para la innovación, 2018. ISBN: 978-84-92933-40
  • Cussó L, Musteanu M, Mulero M, Barbacid M, Desco M. Effects of a ketogenic diet on [18F]FDG -PET imaging in a mouse model of lung cancer. Mol Imaging Bio, 2018
  • Fernández T, Martínez-Serrano A, Cussó L, Desco M, Ramos-Gómez M. Functionalization and Characterization of Magnetic Nanoparticles for the Detection of Ferritin Accumulation in Alzheimer’s Disease. ACS Chemical Neuroscience, 2018
  • Cioffi M, Trabulo SM, Vallespinos M, Raj D, Amgheib A, Saif J, Perez M, Soriano J, Desco M, Gomez-Gaviro MV, Cussó L, Megias D, Aicher A, Heeschen C. The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1. Oncotarget 28;8(13): 21609-21625, 2017
  • Herraiz JL, Herranz E, Cal-González J, Vaquero JJ, Desco M, Cussó L, Udias JM. Automatic Cardiac Self-Gating of Small-Animal PET Data. Mol Imaging Bio 18(1): 109-16, 2016
  • Cussó, L. Tesis Doctorales: "Advantages and applications of quantitative molecular imaging ". Revista 100cias@uned, Nueva época, n. 7, 2014, pp. 26-28. ISSN: 1989-7189, 2014
  • Vaquero JJ, Montesinos P, Cussó L, García-Vazquez V, Desco M. In-line high resolution PET and 3T MRI hybrid device for preclinical multimodal imaging. EJNMMI Phys. 1 (Suppl 1): A7, 2014
  • Hernández-Porras I, Fabbiano S, Schuhmacher AJ, Aicher A, Cañamero M, Cámara JA, Cussó L, Desco M, Heeschen C, Mulero F, Bustelo XR, Guerra C, and Barbacid M. K-Ras V14I recapitulates Noonan syndrome in mice. PNAS 111(46): 16395-16400, 2014
  • Cussó L, Vaquero JJ, Bacharach S and Desco M. Comparison of treatments to reduce myocardial 18F-FDG uptake in preclinical models: calcium channel blockers versus high-fat diets. PLOS ONE 9(9): e107999, 2014
  • Cussó L, Mirones I, Peña-Zalbidea S, García-Vázquez V, García-Castro J and Desco M. Combination of Single-Photon Emission Computed Tomography and Molecular Resonance Imaging to Track 111In-oxine–labeled Human Mesenchymal Stem Cells in Neuroblastoma-Bearing Mice. Molecular Imaging (13), 2014
  • Ronald JA, Cussó L, Chuang HY, Yan X, Dragulescu-Andrasi A, and Gambhir SS. Development and Validation of Non-Integrative, Self-Limited, and Replicating Minicircles for Safe Reporter Gene Imaging of Cell-Based Therapies. PLoS ONE 8(8): e73138, 2013
  • Montesinos P, Abascal JF, Cussó L, Vaquero JJ and Desco M. Application of the Compressed Sensing Technique to Self-Gated Cardiac Cine Sequences in Small Animals. Magn Reson Med 72(2): 369-380, 2014
  • Mateos-Pérez M, Desco M, Dae MW, García-Villalba C, Cussó L, and Vaquero JJ. Automatic TAC extraction from dynamic cardiac PET imaging using iterative correlation from a population template. Comput Meth Prog Bio 111: 308-314, 2013




Instituto de Investigación Sanitaria Gregorio Marañón
C/ Ibiza 43. Anexo Psiquiatría 1ª planta
28009 Madrid
+34 91 426 5067 Ext 15


Deparment of Bioengineering and Aeroespace Engineering
Universidad Carlos III de Madrid
Avda. de la Universidad, 30
28911 Leganés. Madrid. Spain
+34 91 624 8203